EFFECT OF TREATMENT WITH RAMIPRIL AND DIET SPECIFIC IN DOGS AND CATS WITH CHRONIC RENAL FAILURESummary: OBJECTIVE To evaluate the effect of ACE inhibitor ramipril treatment and diet specific renal jointly and independently in the development of hypertension and renal function during development of the IRC. ANIMALS 71 individuals, 33 of the canine and 41 of the cat species, all diagnosed with IRC. PROCEDURE the IRC was diagnosed in patients from the symptoms, testing and analysis of imaging. Once the diagnosis is confirmed proceeded to make a first measurement of blood pressure, making the second measurement to 15 days of the first and third measurement per month for the second. As the pattern of monthly monitoring for a year. For the imposition of treatment patients were classified in three studies. The 1Â fourth study, patients ranked by their status as hypertensive or not, and by the treatment they received. The 2Â fourth study, patients classified as dietary receiving (regardless of treatment and hypertension). The 3Âş study, patients ranked according to the treatment (regardless of diet and hypertension). RESULTS The results we found that lowers blood pressure (dom) in the group suffer from hypertension receives ramipiril and specific renal diet. The study has not seen a decrease in blood pressure in patients receiving ramipril treatment. Overall survival of the population was 227 days, 309 days for the canine species and 221 for the cat species. The results indicated that there were no deaths among different group of hypertensive patients normotenso is, we must remember that the group of normotensive patients took at least as a preventive dietary treatment, receiving the group of patients with hypertension treatment antihipertensor. The results did not indicate different mortality according to the species in any of the three studies. The results there were no adverse developments in the tension, in the groups of patients who received treatment mixed normotensive (ramipril diet with specific kidney), ramipril treatment only or dietary exclusively. It is noted in the results that the group consisting of all patients (hypertensive and normotensive) treated mixed (ramipril and diet) there is an increase in serum creatinine. The results did not indicate different evolution of renal function between the group treated with diet N / F and the group treated with diet trademark inespecífica for kidney patients. In the comparative study between the ACE inhibitor ramipril and IECa benacepril, in the group receiving ramipril was observed decrease in diastolic blood pressure (dom). CONCLUSIONS set ramipril treatment and diet improves kidney specifically diastolic blood pressure. Longevity in the IRC is not modified depending on the species or sex. The results suggest that treatment ramipril alone or accompanied by specific renal diet and the diet specified for kidney patients by herself, are preventive hypertension in the IRC. There was favorable development of renal function in patients treated with ramipril and IRC specific renal diet. Changes in the composition of the diet N / F, with respect to the composition of other diets mark nonspecific for kidney patients did not alter the evolution of blood pressure and renal function in the IRC. C With the ACE-inhibitors used in the study (ramipril and benacepril) did not obtain improved kidney function. In the study, there was an increased hypotensive effect with the ACE inhibitor ramipril compared with ACE inhibitors benacepril
