RADIOTHERAPY

Author: ANDREU MARTINEZ FRANCISCO JOSE.
Year: 2003.
University: MIGUEL HERNÁNDEZ DE ELCHE [www.umh.es].
Place of defense: MEDICINA.
Place of preparation: UNIVERSIDAD MIGUEL HERNÁNDEZ.

Summary: Sanitation is a service company and as such your organization should be directed to better care for the interests of the user and we must change the organization. No longer are valid organizational schemes based on the profiles care, teaching and research that define traditional specialties. The clinical management deals with the design, implementation and evaluation of the processes of direct patient care, in an appropriate and efficient manner, including the re-engineering of the same if required, underpinned between pillars with the creation and development of Information Systems centered the process of care. Bone information systems santaria. The objective of this research is to develop from the description of the process laid radiotherapy at the Royal Decree 1566/1998 of 17 July, laying down the criteria for quality in radiotherapy Information System, which serves to Management Clinic Comprehensive Services Oncology Radioterápica in order to optimize the treatment of patients on the one hand and complement the information provided by the service management control of each center, and secondly, provide the data required by the latter. Based on the structural and functional distribution of a standard service Oncology Radioterápica develop a flow chart of activity in radiotherapy and radiophysics (Planning), then we can develop a computer application, with the help of Computing Service, which serves as System Management Information Services Clinic Comprehensive Oncology Radioterápica. Moreover, we must get the full involvement in the project, both the direction from the center and end users. PONTO ultimately is the product of the need for integration and coordination of Sciences Oncológicas in general and the Oncology Radioterápica in particular.

Author: MORERA LÓPEZ ROSA M..
Year: 2004.
University: COMPLUTENSE DE MADRID [www.ucm.es].
Place of defense: FACULTAD DE MEDICINA.
Place of preparation: FACULTAD DE MEDICINA.

Summary: INTRODUCTION It is accepted that the reductions radioinducidas in respiratory function tests (PFR), are common in patients receiving radiotherapy (RT) in or around the chest, being more relevant for patients with lung cancer. The usual way in our everyday clinical practice, it pays little attention to pulmonary perfusion. The literature shows that patients with tumors that compress central pulmonary vessels causes perfusion deficit, as these patients to improve their infusion after RT by the mechanism of reperfusion. Objectives To assess the association of the presence of tumor central and hypoperfusion% of reperfusion after RT torácia, on the assumption that the improvement in the PFR should be more common in patients with central tumors and hypoperfusion in other patients. Analyzing influenca the location tumoral-hipoperfusión-reperfusión on lung function tests, and analyzing the evolution of PFR thoracic irradiation after radical. MATERIALS AND METHODS was relizado systematic review (RS) of the scientific evidence on the subject, using the methodology of the Cochrane Collaboration. It has also been picked up a series of 31 patients with prospective cancer d epulmón non small cell treated with locally advanced RT radical, which conducted the study and functional lung perfusion scintigraphy prior to the RT and during follow-up period. CONCLUSIONS The RS has shown great heterogeneity in the selection of variables and the presentation of results. Analyzed articles, most tests show worsening of lung function without being able to know if you have clinical significance and / or statistical, unable to get any conclusions regarding the persufisión by escase results. The number of cases of deteriorating perfusion was significantly lower in patients with central and tumor perfusion deficit significant (p = 0.04), but this phenomenon reperfusion was not accompanied by statistically significant changes in terms of lung function . Perhaps the small sample size may have limited power estadísitica analysis.

Author: FORO ARNALOT PALMIRA.
Year: 2004.
University: AUTÓNOMA DE BARCELONA [www.uab.es].
Place of defense: FACULTAD DE MEDICINA.
Place of preparation: ESCUELA DE POSTGRADO.

Summary: INTRODUCTION The role of radiotherapy in the treatment of painful bone metastases is well established. The dilemma in which this is the best scheme. Randomized studies show that the single dose and fractionated doses are equivalent in their ability antiálgica. However the divided doses continue to be used very often. In our environment there has been no randomized study comparing different patterns of palliative radiotherapy, and the objective of the trial is to compare two schemes palliative radiotherapy 30 Gy in 10 fractions compared with 8 Gy in a fraction. PATIENTS, METHOD AND PURPOSE A randomized clinical trial was requested approval of CEIC to carry it out. The main objective is to demonstrate equality between patterns in terms of the main variables response, relapse, gain efficiency and toxicity. It also conducted a study to assess whether some of the following factors may influence the response: IK, primary tumor, histology, concomitant treatments, and finally locating an economic study simple. It included a total of 160 patients who decided to form multidisciplinary palliative treatment. Pain intensity was collected, following the recommendations of consensus with a categorical scale, the scale was used nominal power by phone. This graduated scale pain from 0 to 10 with 0 absence of pain and 10 pain maximum. It picked up the degree of pain before and after radiotherapy and every three months or until death. Variables that were analyzed were overall response rate (GR considered to be a decrease of two or more of the degree of pain following treatment without increasing needs prior analgesic), complete response (CR was defined as the absence of pain without increasing needs analgesic) relapse (increased pain of two or more on the scale) gain (difference between pain prior and subsequent to radiotherapy) performance (Net) (pain relief quotient between the median duration of response and survival expressed as a percentage) and toxicity was collected according to the scale of the RTOG. RESULTS The measure age was 64.1 + -10.7 years, 57.7% were men and 42.5% women. The most frequent tumor was breast cancer (26.9%), followed by lung cancer (25.6%) and prostate cancer (25%). The most common histology was adenocarcinoma, and the location was more often treated the pelvis (39.4%) and column (36.2%). The overall response rate, complete response, relapse, gain efficiency and toxicity are shown in Table 1. No significant differences were observed between the two patterns studied in any of the main variables. None of the factors considered in the analysis influences the probability of response either studied patterns and the economic cost is 60% more expensive the pattern of 30 Gy that of 8 Gy. Conclusions The data obtained in this series it can be concluded that only a fraction is equivalent in their ability antiálgica that a pattern of 30 Gy, in addition to being more cost to society is more comfortable for the patient.

Author: CAMBRAY AMENÓS MARIA.
Year: 2005.
University: BARCELONA [www.ub.es].
Place of defense: UNIVERSITAT DE BARCELONA.
Place of preparation: UNIVERSITAT DE BARCELONA.

Author: FARRUS LUCAYA M. BLANCA.
Year: 2006.
University: BARCELONA [www.ub.es].
Place of defense: FACULTAD DE MEDICINA - BARCELONA.
Place of preparation: FACULTAD DE MEDICINA - BARCELONA.